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Awad, Issam
One or more keywords matched the following items that are connected to Awad, Issam
Item TypeName
Concept Evaluation Studies as Topic
Concept Cross-Sectional Studies
Concept Drug Evaluation, Preclinical
Concept Feasibility Studies
Concept Mice, Transgenic
Concept Models, Genetic
Concept Mice, Inbred C57BL
Concept Cohort Studies
Concept Multicenter Studies as Topic
Concept Proportional Hazards Models
Concept Mice, Inbred DBA
Concept Case-Control Studies
Concept Mice, Knockout
Concept Cross-Over Studies
Concept Genetic Association Studies
Concept Mice
Concept Logistic Models
Concept Disease Models, Animal
Concept Follow-Up Studies
Concept Longitudinal Studies
Concept Mice, Mutant Strains
Concept Models, Biological
Concept Models, Neurological
Concept Prospective Studies
Concept Retrospective Studies
Academic Article Mixed vascular malformations of the brain: clinical and pathogenetic considerations.
Academic Article Factors predisposing to clinical disability in patients with cavernous malformations of the brain.
Academic Article Misdiagnosis of symptomatic cerebral aneurysm. Prevalence and correlation with outcome at four institutions.
Academic Article Intracranial cavernous malformations: lesion behavior and management strategies.
Academic Article Cerebral vascular malformations adjacent to sensorimotor and visual cortex. Functional magnetic resonance imaging studies before and after therapeutic intervention.
Academic Article A comparison of the clinical profile of cavernous malformations with and without associated venous malformations.
Academic Article Comparative localization of auditory comprehension by using functional magnetic resonance imaging and cortical stimulation.
Academic Article Failure of the hypotensive provocative test during temporary balloon test occlusion of the internal carotid artery to predict delayed hemodynamic ischemia after therapeutic carotid occlusion.
Academic Article Stereotactic computed tomographic-guided aspiration and thrombolysis of intracerebral hematoma : protocol and preliminary experience.
Academic Article Impact of Guglielmi detachable coils on outcomes of patients with intracranial aneurysms treated by a multidisciplinary team at a single institution.
Academic Article AHA Scientific Statement: Recommendations for the management of intracranial arteriovenous malformations: a statement for healthcare professionals from a special writing group of the Stroke Council, American Stroke Association.
Academic Article Spine patient outcomes research trial.
Academic Article Neuroendovascular interventions for intracranial posterior circulation disease via the transradial approach: technical case report.
Academic Article How frequently should we follow small asymptomatic intracranial aneurysms?
Academic Article Neurological deterioration in a patient with a spinal arteriovenous malformation following lumbar puncture. Case report.
Academic Article Advanced magnetic resonance imaging of cerebral cavernous malformations: part II. Imaging of lesions in murine models.
Academic Article Second operation after the failure of previous resection for epilepsy.
Academic Article Cavernous malformations of the basal ganglia and thalamus.
Academic Article Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity.
Academic Article A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease.
Academic Article Prostacyclin in experimental ischemic models.
Academic Article Drainage efficiency with dual versus single catheters in severe intraventricular hemorrhage.
Academic Article Internal carotid artery occlusion for cavernous segment aneurysm.
Academic Article Resolution of intraventricular hemorrhage varies by ventricular region and dose of intraventricular thrombolytic: the Clot Lysis: Evaluating Accelerated Resolution of IVH (CLEAR IVH) program.
Academic Article Periventricular lesions on MRI. Facts and theories.
Academic Article From mutant mice to "vascular permeability therapy" in cavernous angiomas?
Academic Article Treatment of acute focal cerebral ischemia with prostacyclin.
Academic Article Fasudil decreases lesion burden in a murine model of cerebral cavernous malformation disease.
Academic Article Focal parenchymal lesions in transient ischemic attacks: correlation of computed tomography and magnetic resonance imaging.
Academic Article Cerebral cavernous malformations: clinical insights from genetic studies.
Academic Article Extracranial-intracranial bypass surgery: a critical analysis in light of the International Cooperative Study.
Academic Article Different spectra of genomic deletions within the CCM genes between Italian and American CCM patient cohorts.
Academic Article Outcome predictors and spectrum of treatment eligibility with prospective protocolized management of intracerebral hemorrhage.
Academic Article Genetic heterogeneity of inherited cerebral cavernous malformation.
Academic Article Toward more rational prediction of outcome in patients with high-grade subarachnoid hemorrhage.
Academic Article Extent of mesiobasal resection determines outcome after temporal lobectomy for intractable complex partial seizures.
Academic Article Ruptured superior cerebellar artery aneurysm in a child with bilateral fibromuscular hyperplasia of the renal arteries: case report and review of the literature.
Academic Article Retrograde suction decompression of giant paraclinoid aneurysms using a No. 7 French balloon-containing guide catheter. Technical note.
Academic Article Preliminary report of the clot lysis evaluating accelerated resolution of intraventricular hemorrhage (CLEAR-IVH) clinical trial.
Academic Article Biology of vascular malformations of the brain.
Academic Article Patch angioplasty in carotid endarterectomy. Advantages, concerns, and controversies.
Academic Article Low-dose recombinant tissue-type plasminogen activator enhances clot resolution in brain hemorrhage: the intraventricular hemorrhage thrombolysis trial.
Academic Article Extent of resection in temporal lobectomy for epilepsy. I. Interobserver analysis and correlation with seizure outcome.
Academic Article Natural history of recurrent seizures after resective surgery for epilepsy.
Academic Article Intracarotid amobarbital procedure: I. Prediction of decreased modality-specific memory scores after temporal lobectomy.
Academic Article Reoperation for intractable seizures.
Academic Article Comparison and spacial correlation of interictal HMPAO-SPECT and FDG-PET in intractable temporal lobe epilepsy.
Academic Article Exceptional multiplicity of cerebral arteriovenous malformations associated with hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome).
Academic Article Occult intracranial aneurysms in polycystic kidney disease: screening with MR angiography.
Academic Article MR of hereditary hemorrhagic telangiectasia: prevalence and spectrum of cerebrovascular malformations.
Academic Article Parenchymal perianeurysmal cystic changes in the brain: report of five cases.
Academic Article What genes can teach us about human cerebrovascular malformations.
Academic Article Minimally invasive surgery plus recombinant tissue-type plasminogen activator for intracerebral hemorrhage evacuation decreases perihematomal edema.
Academic Article Recommendations for the management of patients with unruptured intracranial aneurysms: A statement for healthcare professionals from the Stroke Council of the American Heart Association.
Academic Article Evaluation of iron content in human cerebral cavernous malformation using quantitative susceptibility mapping.
Academic Article Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations.
Academic Article Prediction of cognitive change as a function of preoperative ability status among temporal lobectomy patients seen at 6-month follow-up.
Academic Article Determinants of external ventricular drain placement and associated outcomes in patients with spontaneous intraventricular hemorrhage.
Academic Article Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling.
Academic Article B-Cell Depletion Reduces the Maturation of Cerebral Cavernous Malformations in Murine Models.
Academic Article Micro-computed tomography in murine models of cerebral cavernous malformations as a paradigm for brain disease.
Academic Article Safety and efficacy of minimally invasive surgery plus alteplase in intracerebral haemorrhage evacuation (MISTIE): a randomised, controlled, open-label, phase 2 trial.
Academic Article RhoA Kinase Inhibition With Fasudil Versus Simvastatin in Murine Models of Cerebral Cavernous Malformations.
Academic Article Thrombolytic removal of intraventricular haemorrhage in treatment of severe stroke: results of the randomised, multicentre, multiregion, placebo-controlled CLEAR III trial.
Academic Article Vascular permeability and iron deposition biomarkers in longitudinal follow-up of cerebral cavernous malformations.
Academic Article Demographic Risk Factors for Vascular Lesions as Etiology of Intraventricular Hemorrhage in Prospectively Screened Cases.
Academic Article Surgical Performance in Minimally Invasive Surgery Plus Recombinant Tissue Plasminogen Activator for Intracerebral Hemorrhage Evacuation Phase III Clinical Trial.
Academic Article Endothelial TLR4 and the microbiome drive cerebral cavernous malformations.
Academic Article Permanent CSF shunting after intraventricular hemorrhage in the CLEAR III trial.
Academic Article Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations.
Academic Article Quantitative susceptibility mapping as a monitoring biomarker in cerebral cavernous malformations with recent hemorrhage.
Academic Article Detection of microbleeds associated with sentinel headache using MRI quantitative susceptibility mapping: pilot study.
Academic Article Phenotypic characterization of murine models of cerebral cavernous malformations.
Academic Article Patients with cranial dural arteriovenous fistulas may benefit from expanded hypercoagulability and cancer screening.
Academic Article Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice.
Academic Article Trial Readiness in Cavernous Angiomas With Symptomatic Hemorrhage (CASH).
Academic Article Influence of Bleeding Pattern on Ischemic Lesions After Spontaneous Hypertensive Intracerebral Hemorrhage with Intraventricular Hemorrhage.
Academic Article Plasma Biomarkers of Inflammation Reflect Seizures and Hemorrhagic Activity of Cerebral Cavernous Malformations.
Academic Article Atorvastatin Treatment of Cavernous Angiomas with Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial.
Academic Article Plasma Biomarkers of Inflammation and Angiogenesis Predict Cerebral Cavernous Malformation Symptomatic Hemorrhage or Lesional Growth.
Academic Article Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease.
Academic Article A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis.
Academic Article Intracranial Hypertension and Cerebral Perfusion Pressure Insults in Adult Hypertensive Intraventricular Hemorrhage: Occurrence and Associations With Outcome.
Academic Article Biomarkers of cavernous angioma with symptomatic hemorrhage.
Academic Article A Brain-Targeted Orally Available ROCK2 Inhibitor Benefits Mild and Aggressive Cavernous Angioma Disease.
Academic Article Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations.
Academic Article Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation.
Academic Article Subclinical imaging changes in cerebral cavernous angiomas during prospective surveillance.
Academic Article Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican.
Academic Article Novel Murine Models of Cerebral Cavernous Malformations.
Academic Article A Pooled Analysis of Diffusion-Weighted Imaging Lesions in Patients With Acute Intracerebral Hemorrhage.
Academic Article Cerebrovascular Complications in Early Survivors of Civilian Penetrating Brain Injury.
Academic Article Propranolol inhibits cavernous vascular malformations by ß1 adrenergic receptor antagonism in animal models.
Academic Article Temporal Evolution and Outcomes of Non-Traumatic Intracerebral Hemorrhage in Hospitalized Patients.
Academic Article A Roadmap for Developing Plasma Diagnostic and Prognostic Biomarkers of Cerebral Cavernous Angioma With Symptomatic Hemorrhage (CASH).
Academic Article Longitudinal transcriptomics define the stages of myeloid activation in the living human brain after intracerebral hemorrhage.
Academic Article PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism.
Academic Article Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations.
Academic Article Perfusion and permeability as diagnostic biomarkers of cavernous angioma with symptomatic hemorrhage.
Academic Article Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation.
Academic Article Commentary: Feasibility and Morbidity of Magnetic Resonance Imaging-Guided Stereotactic Laser Ablation of Deep Cerebral Cavernous Malformations: A Report of 4 Cases.
Academic Article Post-Trial Enhanced Deployment and Technical Performance with the MISTIE Procedure per Lessons Learned.
Academic Article Post-Stroke Depression in Patients with Large Spontaneous Intracerebral Hemorrhage.
Academic Article Baseline Characteristics of Patients With Cavernous Angiomas With Symptomatic Hemorrhage in Multisite Trial Readiness Project.
Academic Article Propranolol inhibits cavernous vascular malformations by ß1 adrenergic receptor antagonism in animal models.
Academic Article Association of Intraventricular Fibrinolysis With Clinical Outcomes in Intracerebral Hemorrhage: An Individual Participant Data Meta-Analysis.
Academic Article Rapamycin in Cerebral Cavernous Malformations: What Doses to Test in Mice and Humans.
Academic Article Circulating Plasma miRNA Homologs in Mice and Humans Reflect Familial Cerebral Cavernous Malformation Disease.
Academic Article Evidence-based interconversion of the Glasgow Outcome and modified Rankin scales: pitfalls and best practices.
Academic Article ß1 integrin monoclonal antibody treatment ameliorates cerebral cavernous malformations.
Concept Observational Studies as Topic
Grant Rock Inhibition as Therapy for Cerebral Cavernous Malformation
Grant IMMUNE RESPONSE IN HUMAN CEREBRAL CAVERNOUS MALFORMATIONS
Grant Biomarkers of Cerebral Cavernous Angioma with Symptomatic Hemorrhage (CASH)
Grant Genesis and Progression of Cerebral Cavernous Malformations
Grant Development of BA-1049 for treatment of cerebral cavernous malformation
Grant BIOMARKERS OF BRAIN PERMEABILITY IN HUMAN CEREBRAL CAVERNOUS MALFORMATIONS
Academic Article Impact of socioeconomics and race on clinical follow-up and trial enrollment and adherence in cerebral cavernous malformation.
Academic Article Underlying intracranial atherosclerotic disease is associated with worse outcomes in acute large vessel occlusion undergoing endovascular thrombectomy.
Academic Article mTORC1 Inhibitor Rapamycin Inhibits Growth of Cerebral Cavernous Malformation in Adult Mice.
Academic Article Trial Readiness of Cavernous Malformations With Symptomatic Hemorrhage, Part II: Biomarkers and Trial Modeling.
Academic Article Trial Readiness of Cavernous Malformations With Symptomatic Hemorrhage, Part I: Event Rates and Clinical Outcome.
Search Criteria
  • Preclinical
  • studies
  • using
  • mouse
  • models